Lumi Twin:
Two Reactors, Unlimited Possibilities
Overview
Value Proposition
Whether developing microbial fermentation processes, optimizing mammalian cell cultures, evaluating engineered strains, or executing process characterization studies, Lumi Twin provides the adaptability required by modern biotechnology laboratories.
Lumi Twin transforms traditional bioprocess development by combining flexibility, adaptability, and parallel experimentation into a single intelligent platform. By enabling simultaneous process evaluation, faster optimization, and superior data quality, Lumi Twin empowers researchers to make better decisions, reduce development timelines, and accelerate the path from discovery to production.
Maximize Experimental Flexibility
Run two completely independent bioprocesses simultaneously on a single integrated platform.
Faster Process Optimization
Reduce development timelines by running parallel experiments under identical environmental conditions.
True Process Adaptability
Configure each vessel independently for microbial fermentation, cell culture, synthetic biology, precision fermentation, or scale-down studies.
Features
Double The Hardware, Double The Productivity
Lumi Twin is preconfigured with two complete bioprocess control environments, enabling simultaneous operation of two independent bioreactors on a single platform. Run parallel experiments, compare process conditions, and accelerate development timelines without increasing laboratory footprint.
Standard Configuration Includes:
- 8 Peristaltic Pumps
- 2 pH Sensors
- 2 DO Sensors
- 2 Temperature Control Loops
- 2 Agitation Drives
- 2 Antifoam Control Systems
- Independent Vessel Control and Data Acquisition
Customize Your Hardware, Tailored to Your Process
Freedom to Configure More
Choose from optional hardware enhancements, including up to 8 TMFCs, inline OD measurement, load cells, and application-specific automation packages, to create a system tailored to your bioprocess requirements.
Choose Your Vessel Platform:
- Compatible with a broad range of vessel sizes and geometries.
- Select vessel bundles from the Lumi – FMax glass fermenter series for fermentation.
- Choose Lumi – CMax vessel bundles for cell cultivation.
Intelligent Software for Parallel Bioprocessing
Advanced Comparative Experiment Management
LumiWise software enables researchers to:
- Run independent recipes in both vessels
- Compare live process performance side-by-side
- Monitor critical process variables in real time
- Analyze process trends simultaneously
- Generate comprehensive experimental reports
Advanced Cascade Control
- Loop Cascade
- Time Cascade
- Feed Cascade
- Step Cascade
- Multi-variable Adaptive Control
These powerful automation tools enable dynamic process responses that adapt to changing culture requirements throughout the process cycle.
LumiWise Advanced Automation & Compliance
LumiWise combines powerful automation, intuitive process control, and regulatory-ready compliance in a single platform. Advanced cascade control enables automatic linking of PID loops, allowing DO to dynamically control agitation, oxygen enrichment, or gas flow.
Designed for GMP environments, LumiWise supports 21 CFR Part 11 compliance with electronic records, electronic signatures, audit trails, and role-based access control.
Smarter Automation. Greater Compliance. Better Process Control.
Technical Specifications
Controller & Utilities
| Communications | 2 USB (for software update, serial communication) |
|---|---|
| Power | AC 220V, 50/60 Hz, |
| Water | 10 psig per unit |
| Gas (Air, O2, CO2 and N2) | 20 psig (0.7 bar) |
| Exhaust | 0.5 psig (0.035 bar) |
| Operating Temperature | 10-32°C, no more than 80% relative humidity and no condensation |
System Components
| Agitation | Direct Drive, 25-1200rpm as standard |
|---|---|
| Temperature Control | Water Jacket or Heating Blanket (5°C above coolant temperature to max 60°C) Heating Blanket |
| Probe | Pt100 |
| Gas Sparging & Overlay | Up to 10 total TMFCs for sparger and overlay, ring or microbubble sparger |
| Peristaltic Pumps | Fixed speed (25 rpm) or Variable speed (25-200 rpm) |
Sensors
| pH | 2-12 |
|---|---|
| DO | 0-200% |
| Redox | (- 2000mv) – (+ 2000mv) |
| CO2 | 0 -100% |
| Optional | Total Cell Density, Viable Cell Density, Conductivity, etc. |
Microbial Vessels Design Specifications
| Total Volume |
1L | 3L | 5L | 7L | 10L | 15L |
|---|---|---|---|---|---|---|
| Working Volume |
0.25L – 0.75L | 0.75L – 2.25L | 1.25L – 3.75L | 1.75L – 5.25L | 2.5L – 7.5L | 3.75L – 11.25L |
| Vessel | Single-walled or jacketed | |||||
| Material | Borosilicate glass and 316 stainless-steel | |||||
| Impeller | Rushton | |||||
Cell Culture Vessels Design Specifications
| Total Volume |
2.5L | 5.0L | 7.5L | 14.0L |
|---|---|---|---|---|
| Working Volume |
0.6 – 1.9L | 1.3 – 3.8L | 1.9 – 5.6L | 3.5 – 10.5L |
| Vessel | Single-walled or jacketed | |||
| Material | Borosilicate glass and 316 stainless-steel | |||
| Impeller | Pitched-blade, cell lift, packed-bed basket | |||
Resources
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